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All clinically significant adverse events occurring following administration of rabies biologics should be reported to the Vaccine Adverse Event Reporting System (VAERS), even if causal relation to vaccination is not certain. Although VAERS is subject to limitations common to passive surveillance systems, including underreporting and reporting bias, it is a valuable tool for characterizing the safety profile of vaccines and identifying risk factors for rare serious adverse reactions to vaccines. VAERS reporting forms and information are available electronicallyexternal icon or by telephone via a 24-hour toll-free telephone number, 800-822-7967. Web-based reporting is available and providers are encouraged to report electronicallyexternal icon to promote better timeliness and quality of safety data. 1e1e36bf2d